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May be used once the daily dose has been titrated utilizing typical tablets (when the 8-hour dose of the extended-release preparation corresponds to the titrated 8-hour dose of the standard tablets

Muscle weakness occurred at the start of treatment, but usually disappeared with continued use.

DRUG INTERACTIONS: Your doctor or health professional might already bear in mind of any doable drug interactions and should be observation you for them. don’t begin, stop, or amendment the dose of any drugs before checking together with your doctor or health professional initial. Before exploitation this medication, tell your doctor or health professional of all prescription and nonprescription/herbal merchandise you’ll use, particularly of: “blood thinners” (such as warfarin), cyclosporine. Corticosteroids (such as corticoid, prednisone) might increase the risk of edema and heart disease.